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KMID : 0359819950240020181
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Journal of Korean Neurosurgical Society
1995 Volume.24 No. 2 p.181 ~ p.188
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A Study of Therapeutic Modalities of Pineal Region Tumors
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배기한
엄진화/김동희/김대조/강창구/박권희
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Abstract
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The management of pineal region tumors remains controversial. Advocates of a conservative approach emphasize the excellent results of radiotherapy. particularly with germinoma. while a number of recent reports have demonstrated the safety of
direct
surgery.
We analyzed 8 cases of pineal region tumors which had been treated at our institution over the past 7 years. Tissue diagnosis was obtained in 3 patients before irradiation and 5 patients underwent irradiation without histological diagnosis. Among
5
irradiated patients initially. four patients had been achieved complete remission by radiotherapy thus they were presum-ptively germinoma. but other one patient had no response. so the had been underwent surgry. Among 3 biopsy proven cases. 2
were
teratoma and other one was embryonal carcinoma cases.
MRI and other neuroradiological studies have been found to be useful in indicating the biological nature and histological type of pineal tumor. So, consideration of MRI scans together with tumor markers and response to small dose irradiation will
generally allow a specific diagnosis with a high degree of probability. In this way, germinomas may be selected for radiotherapy and the tumor less likely to response may be subject to primary surgery to obtain complete tumor extirpation or
tissue
diagnosis.
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KEYWORD
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